The concentration-time curve of desipramine, the major metabolite of imipramine, fitted in with a one-compartment kinetic model.
主要代谢产物去甲丙咪嗪药时曲线符合一室线性动力学。
Desipramine overdose is more likely to result in death than overdose with other tricyclic antidepressants, notes a company letter sent to healthcare professionals.