However, the recent report of GNAS mutations being detected in a significant proportion of parosteal osteosarcoma challenges the specificity of this mutation.
然而,最新的检测报道发现在很大一部分骨旁骨肉瘤中有GNAS突变,对该基因突变的特异性提出了质疑。
Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.